Table 2. Plasma levels of circulating miRNAs in children with CHB relative to healthy controls.

miRNA	Sample	Mean CT	SD	Foldchange	SE	P-value*
99a	HBeAg pos	26.2	1.4	24	20–30	<0.0001
	HBeAg neg	29.5	1.8	4	3–5
	Control	30.7	1.2	1
100	HBeAg pos	30.4	2.2	114	88–147	<0.0001
	HBeAg neg	33.9	2.2	16	11–24
	Control	37.2	1.6	1
122	HBeAg pos	21.8	1.6	171	132–222	<0.0001
	HBeAg neg	25.3	2.5	23	15–37
	Control	29.1	1.9	1
122 *	HBeAg pos	28.3	1.8	1208	859–1697	<0.0001
	HBeAg neg	32.0	2.9	141	81–247
	Control	38.5	2.6	1
125b	HBeAg pos	26.8	1.5	12	10–15	<0.0001
	HBeAg neg	29.9	1.6	2	2–3
	Control	30.3	1.1	1
192	HBeAg pos	25.1	1.5	29	23–37	<0.0001
	HBeAg neg	28.2	1.5	5	4–7
	Control	29.9	1.3	1
192 *	HBeAg pos	31.7	1.5	113	85–150	<0.0001
	HBeAg neg	35.1	1.9	17	11–26
	Control	38.5	1.9	1
193b	HBeAg pos	28.9	1.6	19	15–24	<0.0001
	HBeAg neg	32.0	1.6	3	2–5
	Control	33.1	1.2	1
194	HBeAg pos	26.6	1.8	75	62–92	<0.0001
	HBeAg neg	29.9	1.3	12	9–15
	Control	32.7	0.9	1
215	HBeAg pos	26.4	1.7	38	32–46	<0.0001
	HBeAg neg	29.8	1.5	6	4–8
	Control	31.6	0.9	1
365	HBeAg pos	28.7	1.6	20	17–23	<0.0001
	HBeAg neg	31.6	1.4	4	3–5
	Control	32.9	0.8	1
455-5p	HBeAg pos	32.2	1.8	28	7–115	<0.0001
	HBeAg neg	35.7	1.8	4	3–5
	Control	36.8	1.3	1
455-3p	HBeAg pos	28.2	1.7	63	50–79	<0.0001
	HBeAg neg	31.5	2.2	10	7–14
	Control	34.1	1.5	1
483-3p	HBeAg pos	32.3	2.1	27	22–34	<0.0001
	HBeAg neg	35.2	1.9	6	4–8
	Control	36.9	0.9	1
885-5p	HBeAg pos	29.4	1.7	168	137–205	<0.0001
	HBeAg neg	33.0	2.0	22	15–30
	Control	36.7	1.1	1
1247	HBeAg pos	34.4	2.4	20	15–27	<0.0001
	HBeAg neg	37.5	1.7	5	4–7
	Control	38.6	1.1	1

Footnote:

^*HBeAg positive versus HBeAg negative. HBeAg positive versus controls and HBeAg negative versus controls were all significant at p<0.0001, except for miR-125b HBeAg negative versus controls (p = 0.005) and miR-1247 HBeAg negative versus controls (p = 0.002).