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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Eur J Med Chem. 2012 Dec 5;60:456–468. doi: 10.1016/j.ejmech.2012.11.041

Table 3.

Solubilities of the N5-2OH, 3e, 3f, 9b1/2-9d1/2 and 11b1/2-11d1/2 in PBS at pH 7.4 at 25 °C.

Compounds PBS pH 7.41 Compounds PBS pH 7.41
N5-2OH 7-10 |g/mL 9d1/2 33.9 ± 1.4 |g/mL
3e >19.5 mg/mL 11b1/2 42.6 ± 1.0 |g/mL
3f >15 mg/mL 11c1/2 25.4 - 26.3 |g/mL2
9b1/2 133.1 ± 5.2 |g/mL 11d1/2 13.3 - 13.8 |g/mL*
9c1/2 84.2 ± 4.1 |g/mL
1

Standard deviations are based on three experiment

*

Data represent duplicate measurements