Table 3.
Multivariable analysis of risk factors for delayed diagnosis
| Risk factor | Prolonged patient delay (≥23.5 days)* aOR (95%CI)  | 
Prolonged health care delay (≥14 days) aOR (95%CI)  | 
Prolonged total delay (≥59.5 days) aOR (95%CI)  | 
|---|---|---|---|
| Female | 3.03 (1.24–7.40)† | 1.62 (0.65–4.01) | 3.32 (1.40–7.91)† | 
| Age (per year) | 0.99 (0.97–1.01) | 1.02 (0.99–1.05) | 1.01 (0.99–1.04) | 
| History of incarceration | — | 0.65 (0.25–1.68) | 0.63 (0.24–1.65) | 
| Household income ≤US$180 | 1.81 (0.98–3.35) | 1.11 (0.58–2.14) | 1.19 (0.64–2.21) | 
| Any tobacco use | 3.13 (1.31–7.48)† | 0.83 (0.36–1.95) | 1.23 (0.54–2.81) | 
| Any comorbidity | 2.24 (1.19–4.24)† | 0.87 (0.45–1.67) | 1.36 (0.74–2.52) | 
| Chronic cough >6 months | 4.71 (1.75–12.69)† | 1.5 (0.58–2.14) | 12.20 (3.73–39.92)† | 
| Hemoptysis | 2.66 (1.33–5.31)† | 0.58 (0.30–1.15) | 1.45 (0.74–2.82) | 
| First symptom included cough | 0.36 (0.19–0.67)† | 0.89 (0.46–1.71) | 0.54 (0.29–1.00) | 
| Multiple first symptoms | 0.51 (0.27–0.97)† | 1.24 (0.64–2.44) | 0.41 (0.21–0.78)† | 
| Self-medicated | 2.53 (1.32–4.86)† | — | — | 
| Prescribed medication | — | — | 2.28 (1.09–4.79)† | 
| Prescribed antibiotics | — | 4.16 (1.97–8.79)† | — | 
| Traditional remedy use | 3.09 (0.80–11.89) | 2.67 (0.70–10.24) | 3.88 (0.96–15.65) | 
| Pre-TB diagnosis of pneumonia/bronchitis/URI | — | 2.1 (0.96–4.58) | 0.68 (0.32–1.45) | 
| Patient delay | — | 0.38 (0.19–0.74)† | — | 
Prolonged delay defined as delay greater than or equal to the median.
Statistical significance at P ≤ 0.05.
aOR = adjusted odds ratio; CI = confidence interval; TB = tuberculosis; URI = upper respiratory infection.