Table 2. ADC changes during hypoxia.

	Normoxia		Two days hypoxia		Seven days hypoxia
	no-AMS	AMS	no-AMS	AMS	no-AMS	AMS
	(n=8)	(n=6)	(n=8)	(n=6)	(n=8)	(n=6)
Basal ganglia	681±21	685±33	693±20	677±41	695±18	691±25
	667–696	659–711	679–707	644–709	683–708	671–712
Gray matter	672±56	715±29	705±40	687±51	688±54	712±39
	633–710	692–738	677–733	646–728	651–725	681–743
White matter	669±48	709±51	684±37	704±35	684±33	725±55
	636–703	668–750	659–709	676–732	661–706	680–769
CC splenium	640±81	626±60	650±55	644±63	665±20	664±37
	584–696	578–675	612–688	594–694	651–679	635–694
CC genu*	675±50	783±118	721±88	731±48	725±45	729±62
	640–710	688–877	660–782	693–769	694–756	679–788

MRI, magnetic resonance imaging. MRI measures of apparent diffusion coefficient (ADC) × 10⁻⁶ mm²/s during normoxia and after 2 days and 7 days sustained hypoxia for five cerebral regions (see Figure 1 for details of regions, CC splenium and CC genu=splenium and genu of the corpus callosum). Data are mean±1 s.d., and 95% confidence limits. Data analyzed using ANOVA for repeated measures. *Significant ADC changes in genu of corpus callosum (P<0.05, for main effect of duration of hypoxia). Similar trend in basal ganglia (P=0.06). Other differences in ADC were not significant.