Table 3. T_2,index changes during hypoxia.

	Normoxia		Two days hypoxia		Seven days hypoxia
	no-AMS	AMS	no-AMS	AMS	no-AMS	AMS
	(n=8)	(n=6)	(n=8)	(n=6)	(n=8)	(n=6)
Basal ganglia	272±44	254±34	266±57	242±13	250±38	243±22
	241–303	227–281	227–305	232–253	224–276	225–261
Gray matter	480±55	526±121	518±132	464±82	477±75	443±85
	442–518	430–623	426–609	398–530	425–529	375–511
White matter*	283±56	294±54	318±86	269±33	290±60	268±31
	245–322	251–338	258–378	243–295	248–332	243–292
CC splenium	327±38	317±50	340±93	299±28	333±47	288±24
	301–354	277–357	276–405	277–322	300–366	269–307
CC genu*	413±80	453±59	432±111	409±90	421±61	290±63
	358–468	406–500	356–509	337–481	378–463	239–340

MRI, magnetic resonance imaging; ROI, region of interest.

MRI measures of T_2,index during normoxia and after 2 days and 7 days sustained hypoxia for five cerebral regions (index is quotient of T₂ signal in each ROI and T₂ signal in cerebrospinal fluid (CFS) in ventricles—see text for details. CC splenium and CC genu=splenium and genu of the corpus callosum). Data are mean±1 s.d., and 95% confidence limits. Data analyzed using ANOVA for repeated measures. *Significant T₂ changes in genu of corpus callosum (P<0.05 for main effect of duration of hypoxia, and duration × AMS interaction), and in white matter (P<0.05 for duration × AMS interaction). Other differences in T_2,index were not significant.