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. 2013 Mar 4;200(5):605–617. doi: 10.1083/jcb.201206121

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© 2013 Dreesen et al.

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Figure 2. — Loss of LMNB1 and LAP2 during normal skin aging and terminal keratinocyte differentiation in vivo. (a and b) Immunohistochemistry of paraffin sections of normal human skin from young (1 yr; a) versus old (>60 yr; b) individuals. Antibodies are LMNB1 (LB1), LAP2, LAP2-α, LMNA/C (LA/C), Ki-67, keratin-10, and negative control (−ctrl). Different skin layers are indicated: stratum corneum (sc), basal layer (bl), and dermis (d).