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. 2013 Feb 8;14(2):3802–3816. doi: 10.3390/ijms14023802

Figure 6.

Figure 6

(a) Overexpression of miR-17~92 in HEK293 cells inhibited the luciferase activity of the PTEN 3′-UTR reporter plasmid. The 3′-UTR reporter plasmids PTEN or PTEN mut were co-transfected with TMP2-miR-17~92 into HEK293 cells. The activity of firefly luciferase was normalized to that of Renilla luciferase. (b) Overexpression of miR-17~92 in HEK293 cells inhibited the luciferase activity of the BIM 3′-UTR reporter plasmid. The 3′-UTR reporter plasmids B1, B2 orB3 were co-transfected with TMP2-miR-17~92 into the HEK293 cells. The activity of firefly luciferase was normalized to that of Renilla luciferase. * p < 0.05 compared with the control.