Table 2.
Effect of Tribendimidine Single and Triple Dosages and Praziquantel in Patients Infected With Clonorchis sinensis in Guangxi, PR China, From June to July 2012 (N = 74)
| Treatment Group |
|||
|---|---|---|---|
| Parameter | Tribendimidine 400 mg Once (n = 25) | Tribendimidine 400 mg Once Daily for 3 d (n = 24) | Praziquantel 75 mg/kg Divided in 3 Doses (n = 25) |
| No. of patients cured (%) | 11 (44) | 14 (58) | 14 (56) |
| No. of patients cured of light infection (%) | 5 (100) | 4 (100) | 4 (100) |
| No. of patients cured of moderate infection (%) | 6 (54) | 10 (59) | 7 (54) |
| No. of patients cured of heavy infection (%) | 0 | 0 | 3 (38) |
| C. sinensis infection intensity | |||
| Overall GM fecal egg counts, EPG | 80.0 | 35.1 | 50.0 |
| Fecal egg counts (range), EPG | (0–3636) | (0–1296) | (0–1876) |
| Egg reduction rate (%) (95% CI) | 97.6 (93.0–98.6) | 98.8 (96.9–99.6) | 98.8 (97.0–99.6) |
Abbreviations: CI, confidence interval; EPG, eggs per gram of stool; GM, geometric mean.