Table 4.

Poststudy Treatment M184V/I Resistance Mutations Detected by Allele-Specific Polymerase Chain Reaction

Mutation	Total (n = 150)	ZDV/3TC (n = 48)	TDF/FTC (n = 46)	LPV/r (n = 56)	P Value
New M184V mutation frequency (%)
No.	134	43	40	51	.181
No new mutation	132 (99%)	41 (95%)	40 (100%)	51 (100%)
New mutation	2 (1%)	2 (5%)	0 (0%)	0 (0%)
<1%	2	2	0	0
New M184I mutation frequency (%)
No.	119	40	34	45	.735
No new mutation	114 (96%)	38 (95%)	32 (94%)	44 (98%)
New mutation	5 (4%)	2 (5%)	2 (6%)	1 (2%)
<1%	5	2	2	1
Any new M184 mutation (%)
No.	134	43	40	51	.344
No new mutation	127 (95%)	39 (91%)	38 (95%)	50 (98%)
New mutation	7 (5%)	4 (9%)	2 (5%)	1 (2%)
<1%	7	4	2	1

Abbreviations: 3TC, lamivudine; FTC, emtricitabine; LPV/r, lopinavir/ritonavir; TDF, tenofovir; ZDV, zidovudine.