Figure 5.

Strand Bias in Signatures of Mutational Processes Extracted from Genic Regions of 21 Breast Cancer Genomes

(A) Four mutational signatures deciphered from the base substitutions (including their immediate 3′ and 5′ sequence context) identified in genic regions of 21 breast cancer genomes.

(B) Sequence context independent summary of strand bias in the four mutational signatures extracted from the 21 breast cancer genomes.

The error bars represent the SD of the contributions for each mutation type for the deciphered signature.