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. 2013 Mar;91(3):382–392. doi: 10.1002/jnr.23161

Fig 4.

Fig 4

D2 and D3 protein levels and D2 activity in the hippocampus of SAMP8 and SAMR1 at different ages. D2 (A) and D3 (B) protein levels quantified by Western blotting with anti-D2 and anti-D3 antibodies, respectively. Immunoreactive bands of D2 and D3 (examples shown in upper panels) in the hippocampus of SAMP8 (solid bars) and SAMR1 (open bars) at different ages were quantified using β-actin as standard and expressed relative to that of SAMR1 at 1 month. Results are expressed as means + SD [n = 6–8 (SAMR1), n = 5–6 (SAMP8)]. *P < 0.05 between age-matched SAMP8 vs. SAMR1. C: D2 enzyme activity in the hippocampus of SAMP8 (solid bars) and SAMR1 (open bars) at 1, 3, and 5 months expressed as means ± SD [n = 6 (SAMR1), n = 5–6 (SAMP8)]. *P < 0.05 between age-matched SAMP8 and SAMR1. #P < 0.05 compared with the value at 1 month of the same strain.