Figure 2.

Effects of SME on leptin (a), TNF-α (b), and IL-6 (c) expression in adipose tissue of chow fed rats and HFD control rats treated with saline (5 mL/kg of body weight), and HFD rats treated with rosiglitazone (HFD-RSG, 3 mg/kg of body weight) or SGE (HFD-SGE, 2 g/kg of body weight). Adipose leptin, TNF-α, and IL-6 were determined using a multiplex rat adipocyte Linoplex kit stated in method section. Data are means ± SEM; n = 10 rats/group. ^† P < 0.05, ^‡ P < 0.01 versus chow control; *P < 0.05 and **P < 0.01 compared with HFD-Con.