Table 1.

Interacting residues in the alpha and beta subunits

Interacting residues in the alpha subunit		Interacting residues in the beta subunit
Amino acid	Domain	Amino acid	Domain
E147, E149	Intracellular linker S0–S1	K3,K4, R11	Intracellular NH2 terminus
N237	Intracellular linker S2–S3	K179, Y183	Intracellular COOH terminus
Y195, S199	S1	Y31	TM1
N201	Extracellular linker S1–S2	Q63,Y74, Q99, D111	Extracellular loop
Y263	Extracellular linker S3–S4	F159	TM2