Table 2.

Summary of second-line Phase II clinical trials of Axitinib in metastatic renal cell carcinoma

References	Previous treatments	Drugs	n	OR (%)	Median PFS (months)	OS (months)
Rini et al22	Sorafenib	Axitinib 5 mg bd	62	22.6	7.4 (95% CI 6.7–11)	13.6 (95% CI 8.4–18.8)
Rixe et al23 and Motzer et al24	Cytokines	Axitinib 5 mg bd	52	44.2	15.7 (95% CI 8.4–23.4)	29.9 (95% CI 20.3–NR)

Abbreviations: CI, confidence interval; NR, not reached; OR, objective response; OS, overall survival; PFS, progression-free survival.