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. 2013 Mar;182(3):776–785. doi: 10.1016/j.ajpath.2012.11.021

Figure 7.

Figure 7

DALDA-induced protection from I/R injury correlates with enterocyte AKT and GSK3β phosphorylation. Mice were treated with DALDA and exposed to I/R, as described in the legend to Figure 2. Healthy tissues (H) represent a nonischemic region of the small bowel adjacent to the damaged area. A: Representative IHC of ileal Swiss rolls stained for p-Akt. N = 2 per group. B: Representative IHC of ileal Swiss rolls stained for p-GSK3β. N = 3 per group. C: Number of p-GSK3β–positive crypts per 10 crypts. N = 3 mice per group, with three random fields of view per mouse. Analysis was performed by one-way analysis of variance with Tukey’s post test. **P < 0.01. Scale bars: 200 μm (A and B).