. Author manuscript; available in PMC: 2013 Dec 5.

Published in final edited form as: Structure. 2012 Nov 8;20(12):2174–2184. doi: 10.1016/j.str.2012.09.021

Table 3.

IC₅₀ Values for Peptide Inhibition JNK Kinase Activity

Protein Substrate	pepJIP	pepATF2	pepSAB
His-SAB (1_–390)	0.21 ± 0.02	53.4 ± 5	6.76 ± 0.94
FLAG-ATF2 (2–115)	0.30 ± 0.07	136.9 ± 41	7.56 ± 1.74

IC₅₀ is displayed in μM. Inhibition of radioactive 33P incorporation by JNK3α1 (39–422) into either His-SAB (1–390) or FLAG-ATF2 (2–115) by pepJIP, pepATF2, or pepSAB.