Table 2:

Rates of hypoglycemia and nocturnal plasma glucose concentrations among 15 patients with type 1 diabetes during each intervention

Outcome	Intervention, no. (%)		p value*
	Dual-hormone closed-loop delivery n = 15	Continuous subcutaneous insulin infusion n = 15
Patients with at least 1 hypoglycemic event†	1 (7)	8 (53)	0.02
Patients with at least 1 nocturnal hypoglycemic event†‡	0 (0)	5 (33)	0.07
Patients with at least 1 exercise-induced hypoglycemic event†§	1 (7)	2 (13)	1.0
Nocturnal‡ plasma glucose measurements¶	n = 363	n = 367
< 4.0 mmol/L	2 (0.5)	45 (12.3)	—
< 3.3 mmol/L	0 (0.0)	13 (3.5)	—
< 3.0 mmol/L	0 (0.0)	9 (2.5)	—

^*McNemar test.

^†Defined as at least 1 measurement of plasma glucose concentration < 3.0 mmol/L, which was treated by oral carbohydrate.

^‡Between the hours of 2300 and 0700.

^§From start of exercise to 1920.

^¶Measurements were taken at 20-min intervals.