Figure 7. Plasma lyso-Gb₃, as well as urine and plasma GL-3 levels in male FD patients after oral administration of migalastat HCl.

(A) Male FD patients who showed urine GL-3 reductions after oral administration of migalastat HCl; (B) male FD patients who did not show urine GL-3 reductions after oral administration of migalastat HCl; ULN, upper limit of normal. The ULN was determined for urine GL-3, and the value is 74.6 pmol/nmol PC. The same acronym denotes the upper range of normal for plasma lyso-Gb₃ (value is 1.12 ng/mL; [36]) and plasma GL-3 (value is 2.50 µg/mL).