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. 2013 Mar 5;8(3):e58370. doi: 10.1371/journal.pone.0058370

Table 1. Sample characteristics stratified by Type D personalitya.

Total(n = 313) Type D(n = 64) non-Type D (n = 249) p
Demographics
Male gender 75.3 (235) 71.9 (46) 76.2 (189) .47
Age (yrs), mean (SD) 65.9 (9.9) 67.2 (10.4) 65.5 (9.8) .25
Living without a partner 25.6 (80) 29.7 (19) 24.6 (61) .41
Affective symptoms
SAD4 score, mean (SD) 2.4 (3.1) 5.4 (3.9) 1.6 (2.3) <.0005
SAD4≥3 33.6 (185) 78.1 (50) 22.0 (54) <.0005
Biomedical risk factors
BMI (kg/m2) b 27.9 (5.0) 28.0 (5.5) 27.9 (4.9) .89
Smoking 22.8 (71) 15.6 (10) 24.6 (61) .13
Hypertension 35.6 (111) 37.5 (24) 35.1 (87) .72
Hypercholesterolemia 54.8 (171) 57.8 (37) 54.0 (134) .59
Diabetes 23.7 (74) 26.6 (17) 23.0 (57) .55
Disease characteristics
Ischemic etiology b 58.1 (180) 53.2 (33) 59.3 (147) .39
LVEF, mean (SD) 31.7 (6.7) 32.2 (6.3) 31.6 (6.8) .53
NYHA class III c 31.7 (99) 35.9 (23) 30.6 (76) .42
Time since diagnosis (yrs), mean (SD) b 7.2 (4.5) 7.7 (5.2) 7.0 (4.2) .23
Interventions
PCI 16.0 (50) 15.6 (10) 16.1 (40) .92
CABG 26.9 (84) 29.7 (19) 26.2 (65) .58
Device therapy d 12.5 (39) 12.5 (8) 12.5 (31) .99
Prescribed medications
Diureticse
Lisdiuretics only 62.2 (194) 76.6 (49) 58.5 (145)
Thiazides only 3.2 (10) 1.6 (1) 3.6 (9) .06
Combined 6.1 (19) 4.7 (3) 6.5 (16)
Beta blockers 66.5 (206) 68.3 (43) 66.0 (163) .73
ACE inhibitors 71.8 (224) 75.0 (48) 71.0 (176) .52
ARB 19.9 (62) 21.9 (14) 19.4 (48) .65
Digoxin 25.3 (79) 32.8 (21) 23.4 (58) .12
Calcium antagonists 13.5 (42) 25.0 (16) 10.5 (26) .002
Oral anticoagulants 47.4 (148) 40.6 (26) 49.2 (122) .22
Aspirin 38.1 (93) 40.6 (26) 37.5 (93) .65
Statins 53.5 (167) 53.1 (34) 53.6 (133) .94
Psychotropic medication 13.8 (43) 18.8 (12) 12.5 (31) .20
Renal function
Renal dysfunction at baseline f 30.4 (95) 31.3 (20) 30.1 (75) .86
GFRcreat at baseline mean (SD) 69.8 (20.3) 69.9 (19.8) 69.8 (23.4) .98
Change in GFRcreat during follow-up mean (SD) −1.6 (15.1) −8.2 (19.7) −0.1 (13.6) .02
a

Results are presented as % (n), unless stated otherwise.

b

Due to missing data for 2–23 patients, analyses were conducted using the available data.

c

NYHA class III versus NYHA class I-II.

d

Either a single, biventricular pacemaker or an implantable cardioverter device.

e

28.1% of patients were not prescribed diuretics. Some patients were prescribed a combination of potassium-sparing diuretics and lisdiuretics (n = 12, 3.6%).

f

GFRcreat<60 mL/min per 1.73 m2.

ARB = angiotensin-II receptor blockers; BMI = body mass index; CABG = coronary artery bypass grafting; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association functional class; PCI = percutaneous coronary intervention; GFRcreat = glomerular filtration rate of creatinine.