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. 2013 Mar 5;8(3):e58345. doi: 10.1371/journal.pone.0058345

Figure 3. Adding malate to the media increased lifespan of C. elegans RNAi knockdown strains.

Figure 3

(A) 10 mM malate increased lifespan of skn-1 RNAi knockdown N2 worms (log-rank p = 0.03). (B) 10 mM malate increased the lifespan of malic enzyme (men-1) RNAi knockdown N2 worms (log-rank p<0.001). (C) 10 mM malate increased the lifespan of mitochondrial malate dehydrogenase (mdh-1) RNAi knockdown N2 worms (log-rank p<0.001). (D) 10 mM malate increased the lifespan of cytoplasmic malate dehydrogenase F46E10.10 RNAi knockdown N2 worms (log-rank p = 0.006).