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. 2013 Mar 5;8(3):e58345. doi: 10.1371/journal.pone.0058345

Figure 5. Malate treatment did not increase the lifespan of sdha-2 and F48E8.3 RNAi knockdown worms.

Figure 5

(A) 10 mM malate increased the lifespan of complex II flavoprotein (sdha-1) RNAi knockdown N2 worms (log-rank p<0.001). (B) 10 mM malate did not increase the lifespan of complex II flavoprotein (sdha-2) RNAi knockdown N2 worms (log-rank p = 0.95). (C) 10 mM malate decreased the lifespan of soluble fumarate reductase F48E8.3 RNAi knockdown N2 worms (log-rank p = 0.002). (D) 10 mM malate increased the lifespan of FAD synthase (flad-1) RNAi knockdown N2 worms (log-rank p<0.001).