Table 1. Process summary of WT CA purification by polymerization.
Sample | Conc (mg/mL) | Vol (mL) | Total protein (g) | % Purity1 | CA yield (g) |
Total cell lysate | 28.1 | 6000 | 168.8 | 15.5 | 26.2 |
ammonium sulfate fraction | 7.9 | 4800 | 38.1 | 69.1 | 26.3 |
1st polymerized fraction | 11.2 | 1600 | 17.9 | 94.4 | 16.9 |
2nd polymerized fraction | 24.7 | 485 | 12.0 | 98.0 | 11.7 |
Q-sepharose flow-through | 21.3 | 490 | 10.5 | 98.3 | 10.3 |
determined using HT Protein Express LabChip in Caliper LabChip GXII system.