Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Total and free lamotrigine clearance during pregnancy
Mean (± SE) total lamotrigine clearance (LTG daily dose [mg/kg]/LTG concentration [mg/L]) and mean (± SE) free lamotrigine clearance (LTG daily dose [mg/kg]/unbound LTG concentration [mg/L]) during nonpregnant baseline and each trimester of pregnancy. * p < 0.001 compared with nonpregnant baseline. δ p < 0.03 compared with first trimester. Cl = clearance.
