Figure 3.

Abundance estimation accuracy and isoform detection recall depending on the acceptable error threshold. (A) Abundance estimation accuracy for correctly predicted isoforms. The three plots show the fraction of correctly estimated isoforms depending on the acceptable error rate (isoforms with error above threshold have incorrect abundances) for high-, medium-, and low-abundance isoforms. While performance is best for high-abundance isoforms for all methods, iReckon outperforms other methods for all three categories and regardless of the error threshold. (B) Isoform detection recall depending on the acceptable error rate (isoforms with error above the threshold are considered “not predicted”). iReckon outperforms the other methods, especially for low-abundance isoforms.