Table 3.
Sensitivity, specificity, positive predictive value, and negative predictive values for different cutoff levels of scores for physical exam findings and symptoms, Zambia, 1995–2009.
| All | |||||
|---|---|---|---|---|---|
| Number of symptoms and PE findings (cutoffs) | Proportion of seroconverting intervals in cutoff | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) |
| 0 | 124/4510 | ||||
| ≥1 | 226/3191 | 64.6 | 59.7 | 7.1 | 97.3 |
| ≥2 | 81/706 | 23.1 | 91.5 | 11.5 | 96.2 |
| ≥3 | 11/79 | 3.1 | 99.1 | 13.9 | 95.6 |
| 4 | 2/6 | 0.6 | 99.9 | 33.3 | 95.5 |
| Men | |||||
|---|---|---|---|---|---|
| Number of symptoms and PE findings (cutoffs) | Proportion of seroconverting intervals in cutoff | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) |
| 0 | 43/1909 | ||||
| ≥ 1 | 116/1833 | 73.0 | 52.1 | 6.3 | 97.7 |
| ≥ 2 | 48/511 | 30.2 | 87.1 | 9.4 | 96.6 |
| ≥ 3 | 10/63 | 6.3 | 98.5 | 15.9 | 95.9 |
| 4 | 1/4 | 0.6 | 99.9 | 25.0 | 95.8 |
| Women | |||||
|---|---|---|---|---|---|
| Number of symptoms and PE findings (cutoffs) | Proportion of seroconverting intervals in cutoff | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) |
| 0 | 81/2601 | ||||
| ≥ 1 | 110/1358 | 57.6 | 66.9 | 8.1 | 96.9 |
| ≥ 2 | 33/195 | 17.3 | 95.7 | 16.9 | 95.8 |
| ≥ 3 | 1/16 | 0.5 | 99.6 | 6.3 | 95.2 |
| 4 | 1/2 | 0.5 | 100.0 | 50.0 | 95.2 |
*
Physical exam findings and symptoms include chronic diarrhea, malaria syndrome, night sweats, and any bilateral adenopathy