Table 4.
Antecedents of Subsequent Diagnostic Shifts in Psychotic Disorders: Structural Equation Modeling
| Fit Indicesa |
Path coefficientsb |
|||||
|---|---|---|---|---|---|---|
| CFI | TLI | RMSEA | Baseline to month 6 |
6 months to year 2 |
Year 2 to year 10 |
|
| Schizophrenia spectrum disorders | ||||||
| GAF | 0.994 | 0.996 | 0.055 | −0.25*** | −0.06 | −0.13* |
| Negative symptoms | 0.991 | 0.994 | 0.064 | 0.29*** | 0.10 | 0.16** |
| Psychotic symptoms | 0.996 | 0.996 | 0.054 | 0.09* | −0.01 | 0.11* |
| Depression symptoms | 0.986 | 0.982 | 0.106 | −0.08 | −0.05 | 0.08 |
| Antipsychotics | 0.999 | 0.999 | 0.021 | 0.04 | 0.00 | 0.07 |
| Bipolar disorder | ||||||
| GAF | 0.994 | 0.996 | 0.049 | 0.32*** | 0.04 | 0.13* |
| Negative symptoms | 0.993 | 0.996 | 0.055 | −0.34*** | 0.00 | −0.16* |
| Psychotic symptoms | 0.986 | 0.983 | 0.108 | 0.01 | 0.00 | −0.10 |
| Depression symptoms | 0.987 | 0.984 | 0.098 | −0.14** | 0.03 | −0.12* |
| BPRS excitement | 0.984 | 0.979 | 0.116 | 0.13** | 0.07 | −0.08 |
| Anti-manic medication | 0.996 | 0.997 | 0.051 | 0.18*** | 0.15* | −0.03 |
| Major depression | ||||||
| GAF best | 0.987 | 0.986 | 0.077 | 0.03 | 0.00 | 0.09 |
| Negative symptoms | 0.980 | 0.978 | 0.096 | −0.04 | 0.02 | −0.06 |
| Psychotic symptoms | 0.991 | 0.987 | 0.072 | −0.28*** | 0.03 | −0.12 |
| Depression symptoms | 0.984 | 0.982 | 0.086 | 0.36*** | 0.09 | −0.08 |
| Anti-depressants | 0.994 | 0.993 | 0.056 | 0.27*** | −0.12 | 0.01 |
| Anti-manic medication | 0.994 | 0.992 | 0.061 | −0.15* | −0.15 | 0.08 |
| Subtance-induced disorder | ||||||
| Substance treatment | 0.996 | 0.995 | 0.026 | 0.25*** | 0.20 | −0.03 |
NOTE. Variables were selected from significant associations found in the mixed-effects logistic regression analyses.
CFI = Comparative Fit Index; TLI = Tucker Lewis Index; RMSEA = Root Mean Square Error of Approximation.
Standardized path coefficient for the symptom or treatment characteristic at one wave to the diagnostic status at the next wave, controlling for diagnosis at the former wave.
p<0.05
p<0.01
p<0.001