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. Author manuscript; available in PMC: 2013 Mar 6.
Published in final edited form as: Am J Psychiatry. 2011 Jun 15;168(11):1186–1194. doi: 10.1176/appi.ajp.2011.11010048

Table 4.

Antecedents of Subsequent Diagnostic Shifts in Psychotic Disorders: Structural Equation Modeling

Fit Indicesa
Path coefficientsb
CFI TLI RMSEA Baseline to
month 6
6 months to
year 2
Year 2 to
year 10
Schizophrenia spectrum disorders
  GAF 0.994 0.996 0.055 −0.25*** −0.06 −0.13*
  Negative symptoms 0.991 0.994 0.064   0.29***   0.10   0.16**
  Psychotic symptoms 0.996 0.996 0.054   0.09* −0.01   0.11*
  Depression symptoms 0.986 0.982 0.106 −0.08 −0.05   0.08
  Antipsychotics 0.999 0.999 0.021   0.04   0.00   0.07
Bipolar disorder
  GAF 0.994 0.996 0.049   0.32***   0.04   0.13*
  Negative symptoms 0.993 0.996 0.055 −0.34***   0.00 −0.16*
  Psychotic symptoms 0.986 0.983 0.108   0.01   0.00 −0.10
  Depression symptoms 0.987 0.984 0.098 −0.14**   0.03 −0.12*
  BPRS excitement 0.984 0.979 0.116   0.13**   0.07 −0.08
  Anti-manic medication 0.996 0.997 0.051   0.18***   0.15* −0.03
Major depression
  GAF best 0.987 0.986 0.077   0.03   0.00   0.09
  Negative symptoms 0.980 0.978 0.096 −0.04   0.02 −0.06
  Psychotic symptoms 0.991 0.987 0.072 −0.28***   0.03 −0.12
  Depression symptoms 0.984 0.982 0.086   0.36***   0.09 −0.08
  Anti-depressants 0.994 0.993 0.056   0.27*** −0.12   0.01
  Anti-manic medication 0.994 0.992 0.061 −0.15* −0.15   0.08
Subtance-induced disorder
  Substance treatment 0.996 0.995 0.026   0.25***   0.20 −0.03

NOTE. Variables were selected from significant associations found in the mixed-effects logistic regression analyses.

a

CFI = Comparative Fit Index; TLI = Tucker Lewis Index; RMSEA = Root Mean Square Error of Approximation.

b

Standardized path coefficient for the symptom or treatment characteristic at one wave to the diagnostic status at the next wave, controlling for diagnosis at the former wave.

*

p<0.05

**

p<0.01

***

p<0.001