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. 2013 Jan 24;27(3):524–535. doi: 10.1210/me.2012-1330

Figure 2.

Figure 2.

GHR deletion in adipose tissue increases total body fat mass. Two cohorts of mice were studied, including 63 mice (n = 15–16 animals per group) that were used to measure body composition at 6 months of age before a 6-month dissection (A–D) and 83 mice (n = 16–25 animals per group) that were used to measure body composition over time (E–J). For the 63 mice used for dissections, body weight (A), fat mass (B), lean mass (C), and fluid mass (D) are shown for FaGHRKO (FFCx; black bars) and controls (FFxx; white bars) in both males and females. Body weight (E and H), fat mass (F and I), and lean mass (G and J) are shown for males and females over time. FaGHRKO (FFCx; black boxes) and controls (FFxx; white circles) are indicated. Values in A–J are represented as mean ± SEM (n = 15–25 per group). *P < .05; **P < .01; ***P < .001, FaGHRKO (FFCx) vs control (FFxx). BW, body weight.