Table 3.

Functional predictions of AASs in Human Chromosome 22.

Name of tools	Classifications	Number of AAS	MSAC score	PASE physicochemical score	PASEC scores
SIFT	Tolerated	1987	0.47	0.39	0.18
	Deleterious	1351	0.6	0.51	0.3
PolyPhen	Benign	1637	0.44	0.37	0.16
	Possibly damaging	539	0.56	0.43	0.24
	Probably damaging	1162	0.63	0.53	0.33