Table 4.

Proportion of AAS’s with deleterious/damaging predictions from the SIFT/PolyPhen algorithm at different PASEC scores.

PASEC score range	SIFT (%)	PolyPhen (%)
0.8	100	100
0.7	100	95
0.6	86.50	91
0.5	80.70	86.60
0.4	67.10	71.60
0.3	61.40	62.70
0.2	55.70	53.30
0.1	47	42.10
0	40	34.80