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. 2013 Mar 6;3:1393. doi: 10.1038/srep01393

Figure 2.

Figure 2

(A): Number of nigral Iba+ microglia at day 2 and day7.WT = WT mice, TLR def = TLR4-deficient mice. Values are expressed as mean ± SEM (*p < 0.05 comparing MPTP-treated group with its saline control, #p < 0.05 comparing MPTP-treated groups of WT and TLR4-deficient mice). (B): MHC II+ cell number in SN after MPTP treatment at day 2. WT = WT mice, TLR def = TLR4-deficient mice. Values are expressed as mean ± SEM (*p < 0.05 comparing MPTP-treated group with its saline control, #p < 0.05 comparing MPTP-treated groups of WT and TLR4-deficient mice). (C): Representative photographs of the SN (Iba-1 staining) of each treatment group at day 2 are shown. TLR4 def = TLR4-deficient mice, WT = wild-type mice. Control = saline treated mice, MPTP = MPTP treated mice. Scale bars = 200 μm. (D): Correlation analysis of TH+- and Iba+-positive cells counts at day 7 in SNpc (r = −0.92, p < 0.001).