. Author manuscript; available in PMC: 2013 Jul 1.

Published in final edited form as: Cancer Causes Control. 2012 Apr 28;23(7):1017–1029. doi: 10.1007/s10552-012-9967-0

Table 5.

Odds ratios and 95 % CIs for association of sun exposure at ages 13–21 and VDR rs4516035 genotype with risk of non-Hodgkin lymphoma, overall and by subtype, Mayo case–control study, 2002–2008

VDR rs4516035 genotype	Sun exposure at 13–21								Ordinal sun OR (95 % CI)^b	p interaction^c
	≤3 h/week (reference)		4–7 h/week		8–14 h/week		≥15 h/week
	N_co/N_ca	OR (95 % CI)	N_co/N_ca	OR (95 % CI)	N_co/N_ca	OR (95 % CI)	N_co/N_ca	OR (95 % CI)
All NHL (n = 576)^a
AA	19/14	1.0 (ref)	43/43	1.49 (0.66, 3.38)	142/73	0.70 (0.33, 1.49)	117/40	0.42 (0.19, 0.93)	0.66 (0.53, 0.83)
AG + GG	39/23	0.83 (0.35, 1.98)	112/74	0.88 (0.41, 1.87)	278/177	0.84 (0.41, 1.73)	235/132	0.71 (0.34, 1.48)	0.92 (0.79, 1.07)	0.0063
Diffuse large B-cell lymphoma (n = 99)
AA	19/3	1.00 (ref)	43/6	0.95 (0.21, 4.23)	142/9	0.44 (0.11, 1.77)	117/8	0.46 (0.11, 1.92)	0.70 (0.45, 1.11)
AG + GG	39/5	0.81 (0.17, 3.77)	112/13	0.77 (0.20, 2.98)	278/28	0.68 (0.19, 2.48)	235/27	0.78 (0.21, 2.86)	1.01 (0.76, 1.34)	0.23
Follicular lymphoma (n = 144)
AA	19/2	1.00 (ref)	43/10	2.19 (0.43,11.03)	142/28	1.95 (0.43, 8.92)	117/8	0.70 (0.14, 3.58)	0.80 (0.56, 1.16)
AG + GG	39/3	0.73 (0.11, 4.79)	112/13	1.04 (0.22, 5.04)	278/49	1.70 (0.38, 7.62)	235/31	1.33 (0.29, 6.05)	1.12 (0.86, 1.46)	0.066
Small lymphocytic lymphoma/chronic lymphocytic leukemia (n = 195)
AA	19/5	1.00 (ref)	43/12	1.30 (0.39, 4.30)	142/24	0.64 (0.21, 1.94)	117/16	0.43 (0.14, 1.37)	0.65 (0.46, 0.92)	0.33
AG + GG	39/6	0.66 (0.17, 2.49)	112/31	1.08 (0.36, 3.20)	278/60	0.79 (0.27, 2.25)	235/41	0.57 (0.19, 1.67)	0.83 (0.67, 1.04)

Sample size listed are the numbers of subjects with all data available and therefore included in this analysis of interaction

All models adjusted for age, gender, and family history of NHL

All interaction p values are based upon a likelihood ratio test and treat sun exposure as ordinal