Skip to main content
. Author manuscript; available in PMC: 2013 Mar 6.
Published in final edited form as: Org Biomol Chem. 2012 Oct 29;10(46):9113–9129. doi: 10.1039/c2ob26724a

Figure 2.

Figure 2

Schematic of c-di-GMP signaling in bacteria. c-di-GMP metabolizing enzymes are shown as orange rectangles, c-di-GMP molecules are represented by green circles, and receptors of the second messenger are indicated in teal circles. Similar to the EAL domain, some bacteria also utilize HD-GYP domain proteins to decrease intracellular levels of c-di-GMP. Phenotypic outputs induced by high concentrations of the second messenger are indicated on the bottom left and those induced by low concentrations are indicated on the bottom right.