Table 1.

X-ray data collection and refinement statistics for AFF4-P-TEFb-AMPPNP

DOI: http://dx.doi.org/10.7554/eLife.00327.006

Data collection	AFF4-P-TEFb-AMPPNP
Space group	P212121
Cell dimensions: a, b, c	100.691, 126.298, 195.626
Resolution (Å)*	50-2.94 (2.99–2.94)
Unique reflections*	54,189 (2664)
Rsym (%)*	9.3 (>100)
I/σ(I)*	23.2 (1.3)
Completeness (%)*	100.0 (100.0)
Redundancy*	8.1 (7.5)
Temperature (K)	100
Mosaicity (°)	0.45–0.6
Refinement
Resolution (Å)	48.7-2.94
No. reflections	53,775
Rwork/Rfree	0.207/0.245
No. atoms/B-factors (Å2)
CDK9, molecule 1, 2, 3	2558 (111.9), 2533 (116.3), 2558 (121.6)
Cyclin T1, molecule 1, 2, 3	2003 (121.3), 2024 (123.1), 2001 (118.5)
AFF4, molecule 1, 2, 3	248 (156.3), 421 (161.1), 243 (160.3)
Water	19 (90.1)
Root mean square deviations
Bond lengths (Å)	0.004
Bond angles (°)	0.666
Ramachandran plot†
Favored (%)	94.7
Allowed (%)	4.48
Disallowed (%)	0.78
Protein Data Bank ID	4IMY

^*Values in parentheses are for the highest resolution shell.

^†Values from MOLPROBITY.