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The apoptosis induced by different drug combinations in Gefitinib-resistant NSCLC cell lines. Cells were seeded in 96-well plates, and different drug combinations as indicated were added into the plates for 24 hours, and then the activity of caspase3/7 was assayed with caspase3/7 luminescent assay kit Caspase-Glo. Concentration of compound is as follows: Gefitinib: 10 μM, LY294002:20 μM, and U0126:10 μM.
