FIG. 5.

Acellular fibrin scaffold implants in adult rat myocardium. Immunohistological staining of FXIII (A–C) and aprotinin (D–F) scaffold implants in cross section after 7 days of implantation. Rat endothelial cell antigen (RECA)-1 (A, D), CD45 (B, E), and CD68 (C, F) staining indicate a normal wound-healing response to implants. Inset images in (A) and (D) show RECA-1+ cells (indicated by arrowheads) within and adjacent to fibrin scaffold. Black arrows in all panels indicate fibrin implant material. Scale bars=100 μm (50 μm in insets). Color images available online at www.liebertpub.com/tea