Table 2.

Anatomic structures and MRI features analysed

	Structure	Subdivision	T2 hyperintensity	T1 hypointensity	True lesion
WM	Frontal WM	S/D/P
	Temporal WM	S/D/P
	Parietal WM	S/D/P
	Occipital WM	S/D/P
	Corpus callosum	G/B/S
	Internal capsule	A/P/pt
	Cerebellar WM
	Cerebellar peduncles	S/M/I
	Midbrain	Specify structure
	Pons	Specify structure
	Medulla oblongata	Specify structure
Aspect	T2 homogeneity WM
GM	Cerebral cortex
	Thalamus	Specify structure
	Globus pallidus
	Caudate nucleus
	Putamen
	Dentate nucleus
	Substantia nigra
	Other nuclei	Specify structure
	Cerebellar cortex
Atrophy	Cerebral atrophy
	Cerebellar atrophy

WM = white matter; GM = grey matter; S/D/P = subcortical/deep/periventricular; G/B/S = genu/body/splenium; A/P/pt = anterior/posterior/pyramidal tract only; S/M/I = superior/middle/inferior.

Bold notation indicates that item is included in the statistical analysis.