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. 2012 Oct 3;54(2):210–220. doi: 10.1093/jrr/rrs088

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Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Therapeutic Radiology and Oncology 2012. For commercial re-use, please contact journals.permissions@oup.com

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

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Fig. 2. — Efficacy of TS treatment in preventing DNA damage induced by radiation in splenocytes, peripheral blood cells and thymocytes as assessed with alkaline comet assay. One group of mice (n= 8) received TS treatment (400 mg/kg) 24 h before irradiation and another group (n= 8) received vehicle. Mice were exposed to 9.2 Gy of ⁶⁰Co γ-radiation (LD_90/30dose) and samples were collected 30 min and 4 h after irradiation. Sham irradiated mice (n= 8) were used as controls. Representative areas are shown (×200 magnification) in photomicrographs. A significantly smaller percentage of DNA was found in TS-treated mice compared with vehicle-treated mice. TS-treated mice also had a shorter tail length compared with vehicle-treated mice. *Denotes statistically significant difference between vehicle- and TS-treated groups.