Fig. 3.
The effect of TS administration on the number of BAX-, caspase 3 and cPARP-positive cells in mice exposed to 60Co γ-radiation. Mice treated with TS or vehicle 24 h before exposure to 11-Gy radiation were harvested for jejuna samples 4 h post-irradiation. After fixation and processing, cross-sections of jejunum were analyzed for BAX (left panel), caspase 3 (middle panel) and cPARP (right panel) expression by immunohistochemistry. Representative areas are shown (×600 magnification for BAX and cPARP, and X400 for caspase 3) in photomicrographs. *Denotes statistically significant difference between TS- and vehicle-treated groups. Sham irradiated mice were used as controls (bottom panel).