Table 3.
Variable | Pt. (n) | Overall survival rate |
Progression-free survival rate |
Local (in-field) control rate |
|||
---|---|---|---|---|---|---|---|
2-year (%) | P | 2-year (%) | P | 2-year (%) | P | ||
Performance status | |||||||
0–1 | 22 | 46 | 0.17 | 38 | 0.83 | 95 | 0.27 |
2 | 5 | 80 | 40 | 100 | |||
Tumor size | |||||||
<3 cm | 11 | 88 | 0.0013 | 64 | 0.016 | 100 | 0.41 |
≥3 cm | 16 | 29 | 22 | 93 | |||
Irradiated lesion | |||||||
One lesion | 19 | 52 | 0.28 | 38 | 0.79 | 100 | 0.11 |
Two lesions | 8 | 54 | 43 | 86 | |||
Period between start of first-line treatment and RT | |||||||
<2 years | 16 | 35 | 0.023 | 19 | 0.088 | 93 | 0.40 |
≥2 years | 11 | 80 | 64 | 100 | |||
Total dose of radiation (BED, Gy10) | |||||||
<72 | 13 | 49 | 0.72 | 51 | 0.11 | 92 | 0.68 |
≥72 | 14 | 57 | 26 | 100 | |||
Concurrent chemotherapy | |||||||
Yes | 6 | 0 | 0.31 | NR | 0.23 | 100 | NR |
No | 21 | 57 | 42 | 95 | |||
Hyperthermia | |||||||
Yes | 7 | 0 | 0.89 | NR | 0.73 | 100 | NR |
No | 20 | 56 | 42 | 95 | |||
Objective tumor response | |||||||
CR | 11 | 89 | 0.0044 | 67 | 0.013 | 100 | 0.079 |
PR or NC | 16 | 28 | 21 | 93 | |||
Response to chemotherapy immediately before RT | |||||||
PR | 5 | 100 | 0.019 | 80 | 0.069 | 100 | NR |
NC or PD | 15 | 47 | 34 | 100 |
BED = biologically effective dose; NR = not reached; CR = complete response; PR = partial response; NC = no change.