Table 1. Demographic Characteristics in subjects with gastroesophageal reflux (GER) alone, dyspepsia alone, or dyspepsia-GER overlap.
| Dyspepsia-GER Overlap (n=144) | GER alone (n=260) | Dyspepsia alone (n=200) | Neither GER nor Dyspepsia (n=2913) | |
|---|---|---|---|---|
| Age, mean (± SD) | 58 ± 16 | 59 ± 16 | 60 ± 17 | 61 ± 15 |
| Female (n=1909) | 103 (72%) | 149 (57%) | 141 (71%) | 1516 (52%) |
| Male gender (n=1608) | 41 (28%) | 111 (43%) | 59 (29%) | 1397 (48%) |
| SSC score, mean (SD) | 1.5 ± 0.9 | 1.0 ± 0.7 | 1.2 ± 0.7 | 0.7 ± 0.6 |
| Visiting a physician > 5 times (n=369) | 35 (24%) | 43 (17%) | 42 (21%) | 249 (9%) |
| Medication | ||||
| PPIs (n=708) | 80 (56%) | 109 (42%) | 69 (35%) | 450 (16%) |
| Calcium channel blockers (n=204) | 11 (8%) | 12 (5%) | 16 (8%) | 165 (6%) |
| Antidepressants (n=514) | 40 (29%) | 48 (19%) | 57 (29%) | 369 (13%) |
| Narcotics (n=413) | 34 (24%) | 42 (16%) | 39 (20%) | 298 (10%) |
| Antispasmodics (n=54) | 11 (8%) | 7 (3%) | 9 (5%) | 27 (1%) |
| IBS (n=683) | 81 (56%) | 82 (32%) | 102 (51%) | 418 (14%) |
| Somatic symptom checklist items | ||||
| Headaches, mean (± SD) | 1.4 ± 1.2 | 0.9 ± 1.0 | 1.0 ± 1.1 | 0.6 ± 0.8 |
| Backaches, mean (± SD) | 1.9 ± 1.3 | 1.4 ± 1.2 | 1.7 ± 1.3 | 1.0 ± 1.1 |
| Insomnia, mean (± SD) | 2.0 ± 1.3 | 1.3 ± 1.1 | 1.5 ± 1.2 | 0.9 ± 1.0 |
| General stiffness, mean (± SD) | 1.9 ± 1.4 | 1.7 ± 1.2 | 1.8 ± 1.3 | 1.1 ± 1.1 |
| Dizziness, mean (± SD) | 1.0 ± 1.2 | 0.5 ± 0.9 | 0.6 ± 0.9 | 0.3 ± 0.6 |
| Weakness, mean (± SD) | 1.0 ± 1.3 | 0.5 ± 1.0 | 0.8 ± 1.1 | 0.3 ± 0.7 |
SSC, somatic symptom checklist; PPI, proton pump inhibitors; IBS, irritable bowel syndrome