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. Author manuscript; available in PMC: 2013 Mar 6.
Published in final edited form as: Bone. 2011 Dec 28;50(4):954–964. doi: 10.1016/j.bone.2011.12.013

Figure 6.

Figure 6

HS has minimal anti-coagulant activity compared to heparin. At the indicated concentration, GAG was incubated with antithrombin (AT) before the addition of factor Xa (FXa). Any FXa that was not inhibited by AT was measured photometrically using chromogenic substrate S-2222. Relative inhibition was measured by normalizing the values to that of the treatment group containing no GAG. Significant difference is represented as * p<0.001 when compared to the treatment group containing no GAG.