| D-01 | D-02 | D-03 | D-04 | D-21 | D-23 | |
|---|---|---|---|---|---|---|
| Hamilton Rating Scale for Depression (HRSD)a | X | X | X | Xb | N/A | N/A |
| Montgomery–Åsberg Depression Rating Scale (MADRS) | X | X | X | N/A | X | X |
| Inventory for Depressive Symptomatology-Clinician (IDS-C) | N/A | N/A | N/A | N/A | X | N/A |
| Inventory for Depressive Symptomatology-Self-Rated (IDS-SR) | N/A | X | X | X | X | QIDSc |
| Clinical global Impressions-Severity (CGI-S) and Clinical global Impressions-Improvement (CGI-I) | X | X | X | X | X | X |
Notes:aThe 28 item HRSD scale was used in D-01 and the 24-item scale was used in D-02, D-03, and D-04;
b
the HRSD was collected only at baseline, 12 months, and 24 months in the D-04 study;
c
study D-23 utilized the Quick Inventory for Depressive Symptomatology (QIDS).
Abbreviation: N/A, not applicable.