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. Author manuscript; available in PMC: 2013 Mar 6.
Published in final edited form as: Breast Cancer Res Treat. 2011 Jun 17;130(2):619–626. doi: 10.1007/s10549-011-1628-6

Table 3.

GEP testing and Serious Chemotherapy-associated Adverse Events.

Clinical Recurrence Risk
All Patients Low Moderate High
n 534 60 204 253
Occurrence of adverse event 56 (10.5%) 2 (3.3%) 21 (10.3%) 30 (11.9%)
Received GEP test 138 (25.8%) 15 (25.0%) 106 (52.0%) 14 (5.5%)
Odds Ratio for Serious Chemotherapy-associated Adverse Events (95% confidence interval)
Received GEP test
Unadjusted 0.59
(0.24 – 1.22)
- 0.53
(0.21 – 1.35)
0.56
(0.07 – 4.42)
Adjusted for propensity to
receive a GEP test
0.54
(0.24 – 1.22)
- 0.55
(0.21 – 1.43)
0.56
(0.06 – 4.34)

NOTES: Reference in adjusted analyses is women who did not receive a GEP test. Each woman’s propensity to receive a GEP test was estimated as a function of her age at diagnosis, comorbidity score, year of diagnosis, tumor size, grade, nodal status, estrogen and progesterone receptor status, and HER2 receptor status, and was categorized in tertiles in adjusted model. Models not run for low clinical risk group because of limited sample size.