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. 2013 Jan 3;177(2):116–125. doi: 10.1093/aje/kws321

Table 1.

Characteristics of Multicenter AIDS Cohort Study and Women's Interagency HIV Study Participants Stratified by Human Immunodeficiency Virus Status and Highly Active Antiretroviral Therapy Eraa, 1984–2008

Characteristic MACS (1984–1995)
 MACS (1996–2008)
 WIHS (1996–2008)
HIV-Negative
 HIV-Positive
 HIV-Negative
 HIV-Positive
 HIV-Negative
 HIV-Positive
No. % No. % No. % No. % No. % No. %
Individuals 2,581 2,119 2,034 1,741 634 2,228
Person-years 19,117 11,826 17,262 13,161 4,677 16,359
Person-years before HAART initiation N/A N/A 11,826 100 N/A N/A 3,820 29 N/A N/A 4,904 30
Person-years after HAART initiation N/A N/A 0.45 0 N/A N/A 9,340 71 N/A N/A 11,455 70
Alive at exit of analysis 2,530 98 994 47 1,954 96 1,367 79 581 92 1,548 69
AIDS deaths N/A N/A 1,039 49 N/A N/A 202 12 N/A N/A 372 17
Non-AIDS deaths 51 2 58 3 80 4 84 5 53 8 241 11
Deaths of unknown cause N/A N/A 28 1 N/A N/A 88 5 N/A N/A 67 3
All-cause death rateb 267 9,513 463 2,842 1,133 4,157
White, non-Hispanic 2,313 90 1,734 82 1,544 76 1,066 61 86 14 346 16
High school educationc 2,517 99 2,048 98 1,927 96 1,596 94 420 67 1,402 63
College educationc 1,695 66 1,174 56 1,190 59 785 46 56 9 162 7
Employedc 2,351 91 1,816 86 1,678 83 1,144 66 252 40 598 27
Smoking historyc 1,540 60 1,372 65 1,388 69 1,262 73 492 78 1,632 74
>13 alcoholic drinks/weekc 360 15 302 15 195 10 145 8 61 10 142 6
Injection drug use historyc 97 4 270 13 158 8 290 17 189 30 828 37
Any drug use historyc 2,192 85 1,988 94 1,714 84 1,505 86 535 84 1,783 80
Depressive symptomsc 504 20 477 23 488 24 557 32 259 41 1,092 49
HBV at study entry 107 4 152 7 61 3 118 7 3 0 60 3
HCV at study entry 2 0 16 1 39 2 83 5 111 18 657 29
HBV or HCV at study entry 109 4 168 8 100 5 195 11 114 18 701 31

Abbreviations: AIDS, acquired immune deficiency syndrome; HAART, highly active antiretroviral therapy; HBV, hepatitis B virus; HCV, hepatitis C virus; HIV, human immunodeficiency virus; MACS, Multicenter AIDS Cohort Study; N/A, not applicable; WIHS, Women's Interagency HIV Study.

a Pre-HAART era: 1984–1995; HAART era: 1996–2008.

b All-cause death rate per 100,000 person-years.

c Values at baseline, defined as earliest study visit after age 35 years within the calendar period with specified HIV status.