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. 2012 Nov 21;177(2):142–151. doi: 10.1093/aje/kws200

Table 4.

Adjusted Relative Risks and 95% Confidence Intervals for Type I and Type II Endometrial Carcinoma in Relation to Personal and Family Medical History in the NIH-AARP Diet and Health Study, 1995–2006

Self-reported (yes) No. of Noncases Subtypes
Type I (n = 1,312)
Type II (n = 138)
No. RRa 95% CI No. RRa 95% CI
 Diabetes 7,491 137 1.24 1.03, 1.49 18 1.67 1.00, 2.79
Pheterogeneityb = 0.25
 First-degree family history of breast cancer 13,590 130 0.80 0.67, 0.96 28 1.93 1.27, 2.93
Pheterogeneityb = 0.002
  First-degree family history of other cancer 39,072 466 1.01 0.90, 1.14 53 1.24 0.87, 1.75
Pheterogeneityb = 0.52

Abbreviations: CI, confidence interval; NIH, National Institutes of Health; RR, relative risk.

a Adjusted for age (continuous), oral contraceptive use (ever/never), menopausal hormone therapy use (ever/never), parity (nulliparous, 1, 2, ≥3 births), body mass index (<30 vs. ≥30 kg/m2), menarche (<13, 13–14, ≥15 years), age at menopause (premenopausal, <45, 45–49, 50–54, ≥55 years), race (white/nonwhite), and smoking status (never, former, current smoker). Unknown/missing was set as a separate category within each factor.

b P value from logistic regression of case-only analysis comparing each risk factor.