. 2010 Jul 22;172(4):419–429. doi: 10.1093/aje/kwq155

Table 4.

Relative Risk of Death From Cardiovascular Disease, Cancer, and All Other Causes According to Leisure Time Spent Sitting and Physical Activity Among Women and Men, Cancer Prevention Study II Nutrition Cohort, 1993–2006

	Cardiovascular Disease			Cancer			Other Causes
	No. of Deaths	Relative Risk^a	95% CI	No. of Deaths	Relative Risk^a	95% CI	No. of Deaths	Relative Risk^a	95% CI
	Women
Sitting in 1992, hours/day
0–<3	833	1.00	Referent	1,284	1.00	Referent	921	1.00	Referent
3–5	1,196	1.20	1.10, 1.32	1,413	1.07	0.99, 1.16	1,172	1.13	1.04, 1.24
≥6	331	1.33	1.17, 1.52	411	1.30	1.16, 1.46	362	1.41	1.25, 1.60
P_trend		<0.0001			<0.0001			<0.0001
Total physical activity in 1992, MET-hours/week
<17.5	370	1.00	Referent	413	1.00	Referent	374	1.00	Referent
17.5–<24.5	224	0.98	0.83, 1.15	260	1.02	0.88, 1.20	215	0.93	0.78, 1.10
24.5–<31.5	400	0.74	0.64, 0.86	536	0.88	0.78, 1.00	446	0.82	0.71, 0.94
31.5–<42	484	0.76	0.67, 0.87	608	0.82	0.73, 0.94	496	0.76	0.67, 0.87
42–<52.5	369	0.72	0.62, 0.84	499	0.83	0.73, 0.95	387	0.74	0.64, 0.85
52.5–<63	224	0.71	0.60, 0.84	328	0.87	0.75, 1.01	220	0.68	0.57, 0.80
≥63	289	0.66	0.56, 0.77	464	0.86	0.75, 0.99	317	0.69	0.59, 0.80
P_trend		<0.0001			0.03			<0.0001
	Men
Sitting in 1992, hours/day
0–<3	1,413	1.00	Referent	1,457	1.00	Referent	1,160	1.00	Referent
3–5	1,911	1.06	0.99, 1.14	1,853	1.05	0.98, 1.12	1,649	1.13	1.04, 1.22
≥6	685	1.18	1.08, 1.30	571	1.04	0.94, 1.15	608	1.33	1.20, 1.47
P_trend		0.0007			0.29			<0.0001
Total physical activity in 1992, MET-hours/week
<17.5	435	1.00	Referent	379	1.00	Referent	372	1.00	Referent
17.5–<24.5	353	0.87	0.75, 1.00	314	0.91	0.78, 1.06	324	0.92	0.79, 1.07
24.5–<31.5	496	0.81	0.71, 0.92	488	0.96	0.84, 1.10	413	0.77	0.67, 0.89
31.5–<42	818	0.86	0.77, 0.97	781	0.98	0.87, 1.11	685	0.81	0.71, 0.92
42–<52.5	638	0.76	0.68, 0.86	636	0.91	0.80, 1.03	583	0.77	0.67, 0.87
52.5–<63	516	0.78	0.68, 0.88	511	0.92	0.81, 1.05	426	0.70	0.61, 0.80
≥63	753	0.77	0.68, 0.87	772	0.95	0.84, 1.07	614	0.68	0.60, 0.78
P_trend		0.0001			0.52			<0.0001

Abbreviations: CI, confidence interval; MET, metabolic equivalent.

Adjusted for age at interview, race, marital status, education, smoking status, body mass index in 1992, alcohol use, total caloric intake, comorbidities score, and total physical activity (for sitting) and hours sitting (for total physical activity).