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. Author manuscript; available in PMC: 2014 Jan 7.
Published in final edited form as: Mol Pharm. 2012 Sep 20;10(1):26–32. doi: 10.1021/mp300238w

Figure 1. Routes, markers, and Inhibitors of endocytic pathways.

Figure 1

Classical routes of endocytosis are shown across the top and their inhibitors are shown below with their effect on each pathway (solid line - confirmed inhibition; dotted line - possible/partial inhibition). Chlorpromazine inhibits internalization involving clathrin., Filipin III and Nystatin block internalization by caveolae. Amiloride inhibits macropinocytosis. Markers of early endosomes are in red (EEA1) and blue (Rab5). Markers of late endosome/lysosome (Rab9, LAMP-2) are in green and orange. Markers of recycling endosome (Rab11) are in purple. Adapted from Rajendran et al.25.