Table 3.
Pharmacological treatment and adherence of individuals with diabetes, hypertension, and hyperlipidemia by achievement of simultaneous control of HbA1c blood pressure, and LDL cholesterol.
| Denver Health (n=5,269) | Kaiser Permanente Colorado (n=23,458) | |||||||
|---|---|---|---|---|---|---|---|---|
| No simultaneous control | Simultaneous control | Total | p-value | No simultaneous control | Simultaneous control | Total | p-value | |
| n=4,413 | n=856 | n=5,269 | n=16,341 | n=7,117 | n=23,458 | |||
| Medication adherence*, mean (sd) / median | 61.2 (23.3) / 62.6 | 72.3 (18.7) / 74.9 | 63.0 (23.0) / 65.2 | <0.0001 | 81.1 (17.9) / 86.5 | 86.1 (13.6) / 90.1 | 82.7 (16.8) / 87.8 | <0.0001 |
| Any medication dispensed in the last 90 days of follow-up* (n(%)) | 3,301 (74.8%) | 635 (74.2%) | 3,936 (74.7%) | 0.70 | 15,117 (92.5%) | 6,713 (94.3%) | 21,830 (93.1%) | <0.0001 |
| Number of hypertensive medications (%)† | ||||||||
| 0 | 8.5 | 9.0 | 8.6 | 0.006 | 14.1 | 10.5 | 13.0 | <0.0001 |
| 1 | 30.9 | 26.3 | 26.3 | 28.4 | 25.2 | 27.4 | ||
| 2-3 | 45.8 | 52.8 | 46.9 | 44.0 | 49.6 | 45.7 | ||
| 4 or more | 14.8 | 12.0 | 14.4 | 13.4 | 14.8 | 13.9 | ||
| Number of oral hypoglycemic medications (%)† | ||||||||
| 0 | 28.1 | 27.1 | 27.9 | <.0001 | 33.4 | 39.8 | 35.4 | <0.0001 |
| 1 | 32.4 | 42.7 | 34.1 | 39.2 | 41.7 | 40.0 | ||
| 2 or more | 39.5 | 30.2 | 38.0 | 27.4 | 18.5 | 24.7 | ||
| Any cholesterol-lowering medication (%)† | 69.0 | 80.2 | 70.8 | <.0001 | 71.4 | 83.3 | 75.0 | <0.0001 |
| Any insulin (%)† | 34.0 | 15.6 | 31.1 | <.0001 | 32.4 | 20.0 | 28.6 | <0.0001 |
*
Any medication for diabetes, hypertension, or hyperlipidemia.
†
Assessed in the 90 days prior to last clinical measurement of any of the three conditions, among individuals with at least one medication for diabetes, hypertension, or hyperlipidemia dispensed in the last 90 days of observation.