Table 1. GvHD clinical Score.

Score	Weight loss	Skin	Activity	Posture	Fur texture
0	<5%	normal	normal	normal	normal
1	5–10%	flaked	reduced	hunched	scrubby
2	10–20%	explicit fur loss	inactive	severely hunched	severely scrubby
3	>20%

Mice were evaluated for clinical signs of GvHD twice weekly according to Table 1 for each category. Individual scoring points were cumulated. Mice were sacrificed when exceeding a cumulative score ≥6.