Figure 3. Time course of phospho-JNK expression in the cochlear lysate following exposure to the intense noise.
The levels of phospho-JNK in the cochlear lysate at 0 h (immediately after the noise exposure; 104.7±7.6), 3 h (167.2±18.1; p<0.01), 6 h (146.4±13.3; p<0.01), 12 h (129.2±10.8; p<0.01), 24 h (127.1±11.8; p<0.01), and 48 h (185.4±13.8; p<0.01) after the noise exposure significantly increased from the control level (100.0±11.8), with the early and late peaks at 3 h and 48 h. (*p<0.01, Kruskal-Wallis test and Mann-Whitney U-test; n = 8 for each time point).